With syns, enough skill points in the spell and mastery, and skill damage bonus items, it is.
In mods like Nez or Zy-el, those high damages can be reached with ease. Hell, some spells go negative and do 0 at some point, with an exception to poison because of the way it works.
When I used to play Nez, I was pretty pissed when my Sorc ended up doing negative Fireball damage. I had to resort to Firebolts. I wasnt a fan of Hydra and Meteor.